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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 450767Generated: October 30, 2026

Hydrogen Bromide → 6-(2-aminoethyl)pyridin-2(1H)-one hydrobromide

https://huagongshe.com/reaction/450767

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrogen BromideHCID 260—
Reactant2-(6-Methoxypyridin-2-yl)ethan-1-amineHCID 21243519—
Product6-(2-aminoethyl)pyridin-2(1H)-one hydrobromideHCID 68450709—

Reaction Conditions

Temperature80 °C

Reaction Steps

To 700 mg of 2-(6-methoxypyridin-2-yl)ethylamine was added 10 ml of a 47% aqueous hydrogen bromide solution, followed by stirring at 80° C. for 60 hours. After evaporating the solvent, the residue was washed with diethyl ether to obtain 1.21 g of a 6-(2-aminoethyl)pyridin-2(1H)-one hydrobromide as a pale brown solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08486970B2
Source datasetuspto-grants-2013_07
ORD IDord-5a9a769524c248808e11331eb4bdd338
Source noteuspto-grants-2013_07