p-Xylyl bromide → HCID 68798725, compound

HRID 450901Notes

Reaction equation

HRID 450901 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:10]=[C:11]([O:16][CH3:17])[C:12]=1[CH:13]([CH3:15])[CH3:14])[C:6]([O:8]C)=O.[CH3:18][C:19]1[CH:26]=[CH:25][C:22]([CH2:23]Br)=[CH:21][CH:20]=1>>[CH3:18][C:19]1[CH:26]=[CH:25][C:22]([CH2:23][C:6]([C:5]2[CH:10]=[C:11]([O:16][CH3:17])[C:12]([CH:13]([CH3:15])[CH3:14])=[C:3]([O:2][CH3:1])[CH:4]=2)([OH:8])[CH2:6][C:5]2[CH:10]=[CH:11][C:12]([CH3:13])=[CH:3][CH:4]=2)=[CH:21][CH:20]=1

Participants

3

Reactant 2

HCID 7721p-Xylyl bromideHCID 24798870344396-17-4

Product 1

HCID 68798725HCID 68798725, compoundYield 20%

Procedure

This material was prepared as a 20% yield from methyl 3,5-dimethoxy-4-i-propylbenzoate and 4-methylbenzyl bromide using the same method as described in example 1 (b). 1HNMR (CDCl3, ppm): δ 1.30 (d, J=7.1 Hz, 6H), 2.31 (s, 6H), 3.02 (d, J=13.5 Hz, 2H), 3.25 (d, J=13.5 Hz, 2H), 3.52 (m, 1H), 3.71 (s, 611), 6.45 (s, 2H), 6.8-7.2 (m, 8H).

Sources & evidence

ORD record
ord-4c1589a52e0a47c781fff6ef000d394f
Source dataset
uspto-grants-2013_07
Patent number
US08487009B2

Reaction notes

Loading…