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HRID451118

反应详情

EQUATION

反应方程式

HRID 451118 的结构方程式

REACTANTS

反应物

2
结构：CN
HCID6329

Methylamine

CH5N

结构：FC(F)(F)c1ccc(C2COCc3c(Cl)nc(Cl)nc32)cc1
HCID58075462

未命名化合物

PRODUCTS

生成物

1
结构：CNc1nc(Cl)nc2c1COCC2c1ccc(C(F)(F)F)cc1
HCID58075640

未命名化合物

PROCEDURE

实验过程

2,4-dichloro-8-(4-(trifluoromethyl)phenyl)-7,8-dihydro-5H-pyrano[4,3-d]pyrimidine (Preparation Z) was reacted as described in Preparation Xa with methanamine to give 2-chloro-N-methyl-8-(4-(trifluoromethyl)phenyl)-7,8-dihydro-5H-pyrano[4,3-d]pyrimidin-4-amine (Preparation Zb). LC-MS (M+H)+=344.1.