HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 131730713, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 1-(1,1-Dimethylethyl) 2-(2-propen-1-yl) (2S,4S)-4-hydroxy-1,2-pyrrolidinedicarboxylate | HCID 58530047 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 131730713 | HCID 131730713 | — |
Reaction Steps
Hydrochloric acid (4.2 M solution in dioxane, 5 mL, 21 mmol) was added to a solution of 2-allyl 1-tert-butyl (2S,4S)-4-hydroxypyrrolidine-1,2-dicarboxylate (1.05 g, 4.87 mmol) in dichloromethane (20 mL). The resulting mixture was stirred at room temperature for 4 hours then concentrated under vacuum to afford the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08487093B2 |
| Source dataset | uspto-grants-2013_07 |
| ORD ID | ord-e9ef578e304c4b9daa02ee2712567ab5 |
| Source note | uspto-grants-2013_07 |