Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Formic Acid | HCID 284 | — |
| Reactant | Tizanidine | HCID 5487 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Product | HCID 86658841 | HCID 86658841 | 87.5% |
Reaction Steps
3.0 g of the tizanidine base (99.15% HPLC) and 1.9 g of 99% formic acid are added to 5 ml of isopropyl alcohol; after short heating to boil a yellowish solution results, from which a precipitated product starts to separate. After cooling to 0-5° C. and aspiration 3.09 g of tizanidine formate are obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08487113B2 |
|---|
| Source dataset | uspto-grants-2013_07 |
|---|
| ORD ID | ord-3cae91c09d6541ca99ef8ef3556355f8 |
|---|
| Source note | uspto-grants-2013_07 |
|---|
