Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Tizanidine | HCID 5487 | — |
| Reactant | Hexanoic Acid | HCID 8892 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 86658843 | HCID 86658843 | 74.5% |
Reaction Steps
To 5 ml of ethanol, 3.0 g of the tizanidine base (99.15% HPLC) and 2.5 g of hexanoic acid are added. After brief heating to boil a yellowish solution results, from which a precipitated product starts to separate. After cooling to 0 to 5° C. and aspiration 3.25 g of tizanidine hexanoate are obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08487113B2 |
|---|
| Source dataset | uspto-grants-2013_07 |
|---|
| ORD ID | ord-b6434f6d602b4003a6cf9b2cf7004701 |
|---|
| Source note | uspto-grants-2013_07 |
|---|
