Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Glycolic Acid | HCID 757 | — |
| Reactant | Tizanidine | HCID 5487 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 86658844 | HCID 86658844 | 72% |
Reaction Steps
To a solution of 3.0 g of glycolic acid in 6 ml of ethanol, 3.0 g of the tizanidine base (99.15% HPLC) are added. After brief heating to boil a solution results, from which a crystalline precipitated product starts to separate. After cooling to 0 to 5° C. and aspiration 2.8 g of tizanidine glycolate are obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08487113B2 |
|---|
| Source dataset | uspto-grants-2013_07 |
|---|
| ORD ID | ord-327becef351a4a8086625f7f7195889f |
|---|
| Source note | uspto-grants-2013_07 |
|---|
