1-[3-(trifluoromethyl)benzyl]-1H-1,2,4-triazol-3-amine → [1-(3-Methyl-[1,2,4]thiadiazol-5-yl)-piperidin-4-yl]-[1-(3-trifluoromethyl-benzyl)-1H-[1,2,4]triazol-3-yl]-amine

Participants

Role	Name	HCID	Charge
Reactant	1-[3-(trifluoromethyl)benzyl]-1H-1,2,4-triazol-3-amine	HCID 7019329	—
Reactant	1-(3-Methyl-1,2,4-thiadiazol-5-yl)piperidin-4-one	HCID 59258510	—
Product	[1-(3-Methyl-[1,2,4]thiadiazol-5-yl)-piperidin-4-yl]-[1-(3-trifluoromethyl-benzyl)-1H-[1,2,4]triazol-3-yl]-amine	HCID 53354730	—

Reaction Steps

Prepared in analogy to example 1 step h) starting from 1-(3-methyl-[1,2,4]thiadiazol-5-yl)-piperidin-4-one (example 1c) and 1-(3-trifluoromethyl-benzyl)-1H-[1,2,4]triazol-3-ylamine. The title compound was obtained as a white solid.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08486967B2
Source dataset	uspto-grants-2013_07
ORD ID	ord-6c4340a40d3a4033931925a3c333f1fa
Source note	uspto-grants-2013_07