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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 451479Generated: October 30, 2026

HCID 67335196, compound → 3-morpholinopyridin-2-amine

https://huagongshe.com/reaction/451479

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 67335196HCID 67335196—
CatalystPalladiumHCID 23938—
SolventEthyl AcetateHCID 8857—
Product3-morpholinopyridin-2-amineHCID 57494525—

Reaction Steps

To a solution of 4-(2-nitropyridin-3-yl)morpholine (155 mg, 741 μmol) in ethyl acetate was added Pd/C 10% (15.5 mg, 146 μmol) and the reaction was hydrogenated under an atmosphere of hydrogen for 3 hours at room temperature. The catalyst was filtered off, washed with ethyl acetate and the solvent was evaporated under reduced pressure. The title compound was obtained as a purple solid (128 mg, 96%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08486967B2
Source datasetuspto-grants-2013_07
ORD IDord-32f459d0445f420eb01e1820048b6ae1
Source noteuspto-grants-2013_07