Hydrochloric Acid → HCID 67342006, compound

Participants

Reaction Steps

To a solution tert-butyl 1-(2-(trifluoromethyl)pyridin-4-yl)piperidin-4-ylcarbamate (314 mg, 0.91 mmol) in dichloromethane (4.5 mL) was added HCl (2 M in diethylether, 2.27 mL, 4.55 mmol) and the reaction mixture was stirred at room temperature for 18 h. The mixture was then filtered and the white precipitate was washed with dichloromethane and diethylether and dried to afford the title compound (201 mg, 90%) as an off white solid.

Provenance & Evidence