1-(6-Methylpyrimidin-4-yl)piperidin-4-amine dihydrochloride → 4-(3-Chloro-4-fluorophenyl)-6-methyl-N-(1-(6-methylpyrimidin-4-yl)piperidin-4-yl)benzo[d]thiazol-2-amine

Participants

Role	Name	HCID	Charge
Reactant	1-(6-Methylpyrimidin-4-yl)piperidin-4-amine dihydrochloride	HCID 67342133	—
Reactant	2-Bromo-4-(3-chloro-4-fluorophenyl)-6-methylbenzo[d]thiazole	HCID 67342405	—
Product	4-(3-Chloro-4-fluorophenyl)-6-methyl-N-(1-(6-methylpyrimidin-4-yl)piperidin-4-yl)benzo[d]thiazol-2-amine	HCID 86656714	—

Reaction Steps

Prepared in analogy to example 207d, starting from 2-bromo-4-(3-chloro-4-fluorophenyl)-6-methylbenzo[d]thiazole and 1-(6-methyl-pyrimidin-4-yl)-piperidin-4-ylamine dihydrochloride. The title compound was obtained as a white solid.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08486967B2
Source dataset	uspto-grants-2013_07
ORD ID	ord-50a7797ad8f9437eb9cd9ea1a6a5bc36
Source note	uspto-grants-2013_07