Phenylboronic Acid → HCID 58398084, compound

HRID 451565Notes

Reaction equation

HRID 451565 reaction equation
Br[C:2]1[CH:7]=[CH:6][N:5]2[N:8]=[C:9]([NH:11][CH:12]3[CH2:17][CH2:16][N:15]([C:18]4[S:22][N:21]=[C:20]([CH3:23])[N:19]=4)[CH2:14][CH2:13]3)[N:10]=[C:4]2[CH:3]=1.[C:24]1(B(O)O)[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1>>[CH3:23][C:20]1[N:19]=[C:18]([N:15]2[CH2:16][CH2:17][CH:12]([NH:11][C:9]3[N:10]=[C:4]4[CH:3]=[C:2]([C:24]5[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=5)[CH:7]=[CH:6][N:5]4[N:8]=3)[CH2:13][CH2:14]2)[S:22][N:21]=1

Participants

3

Reactant 2

HCID 66827Phenylboronic AcidHCID 67344430HCID 67344430, compound

Product 1

HCID 58398084HCID 58398084, compound

Procedure

Prepared in analogy to example 66c from (7-bromo-[1,2,4]triazolo[1,5-a]pyridin-2-yl)-[1-(3-methyl-[1,2,4]thiadiazol-5-yl)-piperidin-4-yl]-amine and phenyl boronic acid. The title compound was obtained as off-white foam.

Sources & evidence

ORD record
ord-a81f0542711441fcae4d5025f58c4ef7
Source dataset
uspto-grants-2013_07
Patent number
US08486967B2

Reaction notes

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