HCID 2762287, compound → HCID 40429894, compound

Participants

Reaction Steps

(S)-2-(Tert-butoxycarbonylamino)-2-methyl-3-phenylpropanoic acid (1.95 g, 6.98 mmol) was hydrogenated under H2 (50 psi), catalyzed by PtO2 (200 mg), in TFA/H2O (30/30 mL) overnight. The catalyst was filtered off and concentrated to give (S)-2-amino-3-cyclohexyl-2-methylpropanoic acid in quantitative yield. MS ESI +ve m/z 186 (M+H).

Provenance & Evidence