HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 59201315, compound → HCID 59201463, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 59201315 | HCID 59201315 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 59201463 | HCID 59201463 | — |
Reaction Steps
A solution of methyl 2-((R)—((R)-1-((1S,2R)-1-cyclohexyl-1-hydroxy-3-(N-methyl-N-(tert-butoxycarbonyl)amino)propan-2-ylcarbamoyl)piperidin-3-yl)(phenyl)methoxy)ethylcarbamate in 20% (V/V) CH2Cl2 (1 mL) was stirred for 1 h. The solution was evaporated under reduced pressure and the residue purified via prep HPLC to afford methyl 2-((R)—((R)-1-((1S,2R)-1-cyclohexyl-1-hydroxy-3-(methylamino)propan-2-ylcarbamoyl)piperidin-3-yl)(phenyl)methoxy)ethylcarbamate (1.01 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08487108B2 |
| Source dataset | uspto-grants-2013_07 |
| ORD ID | ord-13e3029a6c504698a0f21dcefcdec60a |
| Source note | uspto-grants-2013_07 |