反应详情

20 g (85.5 mmol) of the compound from Example 34A are dissolved in 250 ml of anhydrous toluene, and 22.4 g (85.5 mmol) of triphenylphosphine are added. The solution is heated under reflux for 16 h, resulting in the formation of a precipitate. The mixture is allowed to cool, and the precipitate is filtered off. After washing with diethyl ether, the precipitate is dried under reduced pressure. This gives 39 g (92% of theory) of the desired product.

1. temperatureThe solution is heated
2. temperatureunder reflux for 16 h
3. customresulting in the formation of a precipitate
4. temperatureto cool
5. filtrationthe precipitate is filtered off
6. washAfter washing with diethyl ether
7. customthe precipitate is dried under reduced pressure