huagongshe.com
HRID45233

反应详情

EQUATION

反应方程式

HRID 45233 的结构方程式

REACTANTS

反应物

2
结构：Cl
HCID313

Hydrochloric Acid

ClH

结构：CC(C)(C)NS(=O)(=O)c1ccc(-n2[nH]cc(Cc3cccnc3)c2=O)nc1
HCID67454087

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)(C)NS(=O)(=O)c1ccc(-n2[nH]cc(Cc3cccnc3)c2=O)nc1.Cl
HCID86659741

未命名化合物

收率 100%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：ClCCl
溶剂HCID6344

Dichloromethane

CH2Cl2

PROCEDURE

实验过程

To 912 mg of N-tert-butyl-6-[5-oxo-4-(pyridin-3-ylmethyl)-2,5-dihydro-1H-pyrazol-1-yl]pyridine-3-sulfonamide in 20 mL of DCM is added 1 eq. of HCl (4N in dioxane) and the medium is then concentrated under vacuum. 1 g of N-tert-butyl-6-[5-oxo-4-(pyridin-3-ylmethyl)-2,5-dihydro-1H-pyrazol-1-yl]pyridine-3-sulfonamide hydrochloride is obtained in the form of a white powder.

WORKUP

后处理

  1. concentrationthe medium is then concentrated under vacuum