HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetate → ethyl (4-benzyl-1-{5-[ethyl(phenyl)sulfamoyl]pyridin-2-yl}-5-oxo-2,5-dihydro-1H-pyrazol-3-yl)acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetate | HCID 175 | — |
| Reactant | N-ethyl-6-hydrazinyl-N-phenylpyridine-3-sulfonamide | HCID 2095679 | — |
| Reactant | Diethyl 2-benzyl-3-oxopentanedioate | HCID 12200242 | — |
| Product | ethyl (4-benzyl-1-{5-[ethyl(phenyl)sulfamoyl]pyridin-2-yl}-5-oxo-2,5-dihydro-1H-pyrazol-3-yl)acetate | HCID 123772210 | — |
Reaction Steps
According to the process described in Example 1.3, starting with 5 g (17.1 mmol) of diethyl 2-benzyl-3-oxopentanedioate and 5 g (17.1 mmol) of N-ethyl-6-hydrazino-N-phenylpyridine-3-sulfonamide, 3 g of ethyl 4-benzyl-1-{5-[ethyl(phenyl)sulfamoyl]pyridin-2-yl}-5-oxo-2,5-dihydro-1H-pyrazol-3-yl)acetate are obtained in the form of a white powder.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08541455B2 |
| Source dataset | uspto-grants-2013_09 |
| ORD ID | ord-d1346910ee874305bbc5ae3d9da8c090 |
| Source note | uspto-grants-2013_09 |