HuagongsheHuagongshe Chemistry Print Report · For research reference only
Morpholine → 4-{[7-(Methylsulfonyl)-4H-1,3-benzodioxin-2-YL]methyl}morpholine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Morpholine | HCID 8083 | — |
| Reactant | 2-(bromomethyl)-7-(methylsulfonyl)-4H-1,3-benzodioxine | HCID 66886440 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 4-{[7-(Methylsulfonyl)-4H-1,3-benzodioxin-2-YL]methyl}morpholine | HCID 44481902 | — |
Reaction Steps
Preparation according to Example 22 using 2-(bromomethyl)-7-(methylsulfonyl)-4H-1,3-benzodioxine (30 mg, 0.10 mmol), morpholine (0.50 ml, 5.7 mmol) and EtOH (1.0 ml). MS m/z (rel. intensity, 70 eV) 313 (M+, 1), 101 (6), 100 (bp), 77 (4), 56 (6).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08492372B2 |
| Source dataset | uspto-grants-2013_07 |
| ORD ID | ord-3ded948f6e8f42e98859ffa26eff533f |
| Source note | uspto-grants-2013_07 |