N-Methylethylamine → HCID 44482174, compound

HRID 452422Notes

Reaction equation

HRID 452422 reaction equation
Br[CH2:2][CH:3]1[O:8][C:7]2[CH:9]=[C:10]([S:13]([CH3:16])(=[O:15])=[O:14])[CH:11]=[CH:12][C:6]=2[CH2:5][O:4]1.[CH3:17][NH:18][CH2:19][CH3:20]>CCO>[CH3:17][N:18]([CH2:2][CH:3]1[O:8][C:7]2[CH:9]=[C:10]([S:13]([CH3:16])(=[O:15])=[O:14])[CH:11]=[CH:12][C:6]=2[CH2:5][O:4]1)[CH2:19][CH3:20]

Participants

4

Reactant 2

HCID 12219N-MethylethylamineHCID 668864402-(bromomethyl)-7-(methylsulfonyl)-4H-1,3-benzodioxine

Product 1

HCID 44482174HCID 44482174, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Preparation according to Example 22 using 2-(bromomethyl)-7-(methylsulfonyl)-4H-1,3-benzodioxine (30 mg, 0.10 mmol), N-methylethanamine (0.50 ml, 5.8 mmol) and EtOH (1.0 ml). MS m/z (rel. intensity, 70 eV) 285 (M+, 1), 77 (4), 73 (5), 72 (bp), 51 (3).

Workup

  1. customPreparation

Sources & evidence

ORD record
ord-a39f932767fd4d50aa1b4ea48f87edd2
Source dataset
uspto-grants-2013_07
Patent number
US08492372B2

Reaction notes

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