Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Ethylamine | HCID 6341 | — |
| Reactant | 2-(bromomethyl)-5-fluoro-7-(methylsulfonyl)-4H-1,3-benzodioxine | HCID 66887621 | — |
| Solvent | 2,2,4-Trimethylpentane | HCID 10907 | — |
| Product | HCID 44482175 | HCID 44482175 | — |
Reaction Steps
A mixture of 2-(bromomethyl)-5-fluoro-7-(methylsulfonyl)-4H-1,3-benzodioxine (7 mg, 0.021 mmol), ethanamine (0.5 ml, 2 M in MeOH) and EtOH (3 ml) was heated under microwave radiation at 130° C. for 30 min. MS m/z (rel. intensity, 70 eV) 289 (M+, 0.3), 176 (7), 141 (8), 95 (9), 75 (10), 58 (bp).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08492372B2 |
|---|
| Source dataset | uspto-grants-2013_07 |
|---|
| ORD ID | ord-a134c5a98d2c42c2b526b01ae701d9a5 |
|---|
| Source note | uspto-grants-2013_07 |
|---|
