HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diethylamine → N-Ethyl-N-{[5-fluoro-7-(methylsulfonyl)-4H-1,3-benzodioxin-2-YL]methyl}ethanamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diethylamine | HCID 8021 | — |
| Reactant | 2-(bromomethyl)-5-fluoro-7-(methylsulfonyl)-4H-1,3-benzodioxine | HCID 66887621 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | N-Ethyl-N-{[5-fluoro-7-(methylsulfonyl)-4H-1,3-benzodioxin-2-YL]methyl}ethanamine | HCID 44482446 | — |
Reaction Steps
Preparation according to Example 34 using 2-(bromomethyl)-5-fluoro-7-(methylsulfonyl)-4H-1,3-benzodioxine (7 mg, 0.021 mmol), N-ethylethanamine (0.5 ml) and EtOH (3 ml). MS m/z (rel. intensity, 70 eV) 317 (M+, 0.3), 95 (4), 87 (6), 86 (bp), 75 (4), 58 (7).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08492372B2 |
| Source dataset | uspto-grants-2013_07 |
| ORD ID | ord-c2d9f8a0a8664e42892fe2281639b4b6 |
| Source note | uspto-grants-2013_07 |