反应详情

In a solution of 0.8 g of 4-formyl-2-methyl-N-(2,2,2-trifluoroethyl)benzoic acid amide in 10 ml of ethanol and 5 ml of water, 0.3 g of hydroxyamine hydrochloride and 0.4 g of anhydrous sodium acetate were added with stirring at room temperature, and stirred at the same temperature for 30 minutes. After the completion of the reaction, the solvent was distilled off under reduced pressure, and precipitated crystal was filtered off, washed with water and dried to obtain 0.5 g of the aimed product as white crystal.

1. stirringstirred at the same temperature for 30 minutes
2. customAfter the completion of the reaction
3. distillationthe solvent was distilled off under reduced pressure
4. customprecipitated crystal
5. filtrationwas filtered off
6. washwashed with water
7. customdried