1-(1H-Imidazol-1-yl)ethanone → HCID 68663434, compound

Participants

Reaction Steps

A mixture of N-acetylimidazole (264 mg, 2.4 mmol), 1-[4-(trifluoromethoxy)phenyl]-1H-benzimidazole-6-carbohydrazide (672 mg, 2.0 mmol) and tetrahydrofuran (20 mL) was stirred overnight at room temperature, and at 50° C. for 4 hr. The reaction mixture was concentrated under reduced pressure, ethyl acetate was added to the residue, and the precipitate was collected by filtration to give the title compound (614 mg, yield 81%) as colorless crystals.

Provenance & Evidence