反应详情

温度

120 °C

A mixture of 2-[[4-(methylthio)phenyl]amino]isonicotinohydrazide (511 mg, 1.86 mmol) and triethyl orthoacetate (10 mL) was stirred at 120° C. overnight. After cooling, the precipitate was collected by filtration and recrystallized from hexane/ethyl acetate to give the title compound (441 mg, yield 80%) as yellow crystals.

1. temperatureAfter cooling
2. filtrationthe precipitate was collected by filtration
3. customrecrystallized from hexane/ethyl acetate