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HRID452990

反应详情

EQUATION

反应方程式

HRID 452990 的结构方程式

REACTANTS

反应物

2
结构：O=S(Cl)Cl
HCID24386

Thionyl chloride

Cl2OS

结构：O=C(O)c1cc([N+](=O)[O-])cc(C(F)(F)F)c1
HCID616602

3-Nitro-5-(trifluoromethyl)benzoic acid

C8H4F3NO4

PRODUCTS

生成物

1
结构：O=C(Cl)c1cc([N+](=O)[O-])cc(C(F)(F)F)c1
HCID22608399

3-Nitro-5-(trifluoromethyl)benzoyl chloride

C8H3ClF3NO3

PROCEDURE

实验过程

A solution of 3-nitro-5-(trifluoromethyl)benzoic acid (2.00 g, 8.51 mmol) in thionyl chloride (12.4 ml, 170 mmol) was heated at 90° C. for 2 hours. The solution was cooled to room temperature, concentrated, and azeotroped with toluene to provide 3-nitro-5-(trifluoromethyl)benzoyl chloride as a liquid.

WORKUP

后处理

  1. concentrationconcentrated
  2. customazeotroped with toluene