HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 3-Nitro-5-(trifluoromethyl)benzoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 3-Nitro-5-(trifluoromethyl)benzoic acid | HCID 616602 | — |
| Product | 3-Nitro-5-(trifluoromethyl)benzoyl chloride | HCID 22608399 | — |
Reaction Steps
A solution of 3-nitro-5-(trifluoromethyl)benzoic acid (2.00 g, 8.51 mmol) in thionyl chloride (12.4 ml, 170 mmol) was heated at 90° C. for 2 hours. The solution was cooled to room temperature, concentrated, and azeotroped with toluene to provide 3-nitro-5-(trifluoromethyl)benzoyl chloride as a liquid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08492371B2 |
| Source dataset | uspto-grants-2013_07 |
| ORD ID | ord-b4a247cdd43344568779fb562d08b5ea |
| Source note | uspto-grants-2013_07 |