Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 453560Generated: October 30, 2026

Trifluoroacetic acid → HCID 59403217, compound

https://huagongshe.com/reaction/453560

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 86669064HCID 86669064—
SolventDichloromethaneHCID 6344—
ProductHCID 59403217HCID 59403217111.5%

Reaction Steps

tent-Butyl 2-(4-(4-((2,6-dichlorophenethyl)carbamoyl)phenoxy)-3-cyanophenyl)acetate (34 mg, 0.065 mmol) was dissolved in dichloromethane (1 ml) and TFA (1 ml) was added. After stirring for 45 minutes, the mixture was concentrated under reduced pressure to give 2-(3-cyano-4-(4-(2,6-dichlorophenethylcarbamoyl)phenoxy)phenyl)acetic acid (0.034 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08492437B2
Source datasetuspto-grants-2013_07
ORD IDord-da939b7fd26d4376936e8e99e013f185
Source noteuspto-grants-2013_07