HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(4-Chloro-butyl)-2H-[1,2,4]triazine-3,5-dione → HCID 67512578, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(4-Chloro-butyl)-2H-[1,2,4]triazine-3,5-dione | HCID 15817175 | — |
| Reactant | HCID 22349876 | HCID 22349876 | — |
| Solvent | 1-Methylpyrrolidine | HCID 8454 | — |
| Product | HCID 67512578 | HCID 67512578 | — |
Reaction Steps
2-{4-[4-(2-tert-Butyl-6-difluoromethyl-pyrimidin-4-yl)-piperazin-1-yl]butyl}-2H-[1,2,4]triazine-3,5-dione hydrochloride was prepared from 2-(4-chloro-butyl)-2H-[1,2,4]triazine-3,5-dione and 2-tert-butyl-4-piperazin-1-yl-6-difluoromethyl-pyrimidine by analogy to the process described in example 1 using N-methyl-pyrrolidine as solvent.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08492540B2 |
| Source dataset | uspto-grants-2013_07 |
| ORD ID | ord-e5d7c5db8226467e8f66517d28dde1db |
| Source note | uspto-grants-2013_07 |