反应详情

2-{4-[4-(2-tert-Butyl-6-difluoromethyl-pyrimidin-4-yl)-piperazin-1-yl]butyl}-2H-[1,2,4]triazine-3,5-dione hydrochloride was prepared from 2-(4-chloro-butyl)-2H-[1,2,4]triazine-3,5-dione and 2-tert-butyl-4-piperazin-1-yl-6-difluoromethyl-pyrimidine by analogy to the process described in example 1 using N-methyl-pyrrolidine as solvent.