HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → HCID 22030791, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | Ethyl 7-methoxyquinoline-3-carboxylate | HCID 21865246 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 22030791 | HCID 22030791 | 86% |
Reaction Steps
3-Ethoxycarbonyl-7-methoxyquinoline (28 g, 120 mmol) was added to a methanol solution saturated with ammonia. The suspension was stirred at ambient temperature in a glass pressure vessel for 2 weeks. The white solid was collected by filtration, washed with methanol and dried under vacuum to give 3-carbamoyl-7-methoxyquinoline (21 g, 86%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08492560B2 |
| Source dataset | uspto-grants-2013_07 |
| ORD ID | ord-10e318a94480418387df078044af0f0f |
| Source note | uspto-grants-2013_07 |