HCID 136198182, compound → HCID 136198186, compound

Participants

Reaction Steps

A solution mixture of the obtained tert-butyl 2-(2-hydroxy-5-(pyridin-2-yl)benzamido)-4-phenylbenzoate (0.021 g) in methylene chloride (1 mL) and trifluoroacetic acid (0.5 mL) was stirred at room temperature for 1 hour and 10 minutes. The solvent was evaporated under reduced pressure, and water was added to the obtained residue. After adjusting the pH to 7 with a saturated aqueous solution of sodium bicarbonate, the solid substance was collected by filtration to obtain 0.013 g of 2-(2-hydroxy-5-(pyridin-2-yl)benzamido)-4-phenylbenzoic acid as a white solid.

Provenance & Evidence