Sodium Hydroxide → HCID 58508899, compound

HRID 454571Notes

Reaction equation

HRID 454571 reaction equation
[OH-].[Na+:2].[CH2:3]([NH:5][C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=1[C:12]1[CH:20]=[CH:19][C:15]([C:16]([OH:18])=[O:17])=[C:14]([NH:21][C:22](=[O:36])[C:23]2[CH:28]=[C:27]([C:29]3[CH:30]=[N:31][CH:32]=[CH:33][CH:34]=3)[CH:26]=[CH:25][C:24]=2[OH:35])[CH:13]=1)[CH3:4]>C(O)C>[CH2:3]([NH:5][C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=1[C:12]1[CH:20]=[CH:19][C:15]([C:16]([O-:18])=[O:17])=[C:14]([NH:21][C:22](=[O:36])[C:23]2[CH:28]=[C:27]([C:29]3[CH:30]=[N:31][CH:32]=[CH:33][CH:34]=3)[CH:26]=[CH:25][C:24]=2[OH:35])[CH:13]=1)[CH3:4].[Na+:2]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 58508900HCID 58508900, compound

Product 1

HCID 58508899HCID 58508899, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Ethanol (2.0 mL) and a 1 mol/L aqueous solution of sodium hydroxide (0.067 mL) were added to the obtained 4-(2-(ethylamino)phenyl)-2-(2-hydroxy-5-(pyridin-3-yl)benzamido)benzoic acid (0.032 g), followed by stirring at room temperature for 2 hours and 30 minutes. The solvent was evaporated under reduced pressure, and water was added to the obtained residue. The solid substance was collected by filtration to obtain 0.024 g of sodium 4-(2-(ethylamino)phenyl)-2-(2-hydroxy-5-(pyridin-3-yl)benzamido)benzoate as a white solid.

Workup

  1. customThe solvent was evaporated under reduced pressure, and water
  2. additionwas added to the obtained residue
  3. filtrationThe solid substance was collected by filtration

Sources & evidence

ORD record
ord-05c58cbc805b4f40bfa45c7ce857e5aa
Source dataset
uspto-grants-2013_07
Patent number
US08492582B2

Reaction notes

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