Trifluoroacetic acid → HCID 58508674, compound

Participants

Reaction Steps

Trifluoroacetic acid (5 mL) was added to the obtained tert-butyl 2-(2-hydroxy-5-(piperidin-1-yl)benzamido)-4-phenoxybenzoate (0.067 g), followed by stirring at room temperature for 3 hours. The solvent was evaporated under reduced pressure, and water and 2-propanol were added to the residue. After adjusting the pH to 6.0 with a saturated aqueous solution of sodium bicarbonate, the solid substance was collected by filtration to obtain 0.053 g of 2-(2-hydroxy-5-(piperidin-1-yl)benzamido)-4-phenoxybenzoic acid as a light yellow solid.

Provenance & Evidence