反应详情

Trifluoroacetic acid (4.0 mL) was added to the obtained tert-butyl 2-(5-phenylpyridine-3-carboxamido)-4-(thiophen-2-yl)benzoate, followed by stirring at room temperature for 2 hours. The solvent was evaporated under reduced pressure, and diisopropyl ether was added to the obtained residue. The solid substance was collected by filtration to obtain 54 mg of 2-(5-phenylpyridine-3-carboxamido)-4-(thiophen-2-yl)benzoic acid as a white solid.

1. customThe solvent was evaporated under reduced pressure, and diisopropyl ether
2. additionwas added to the obtained residue
3. filtrationThe solid substance was collected by filtration