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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 454764Generated: October 29, 2026

Trifluoroacetic acid → HCID 58508812, compound

https://huagongshe.com/reaction/454764

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 58508786HCID 58508786—
ProductHCID 58508812HCID 58508812—

Reaction Steps

Trifluoroacetic acid (4.0 mL) was added to the obtained tert-butyl 2-(5-phenylpyridine-3-carboxamido)-4-(thiophen-3-yl)benzoate, followed by stirring at room temperature for 1 hour and 30 minutes. The solvent was evaporated under reduced pressure, and diisopropyl ether was added to the obtained residue. The solid substance was collected by filtration to obtain 47 mg of 2-(5-phenylpyridine-3-carboxamido)-4-(thiophen-3-yl)benzoic acid as a white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08492582B2
Source datasetuspto-grants-2013_07
ORD IDord-356934623c2c4e72bbb03ea01fccb331
Source noteuspto-grants-2013_07