Sodium Hydroxide → HCID 58508811, compound

HRID 454765Notes

Reaction equation

HRID 454765 reaction equation
[OH-].[Na+:2].[C:3]1([C:9]2[CH:10]=[C:11]([C:15]([NH:17][C:18]3[CH:26]=[C:25]([C:27]4[CH:31]=[CH:30][S:29][CH:28]=4)[CH:24]=[CH:23][C:19]=3[C:20]([OH:22])=[O:21])=[O:16])[CH:12]=[N:13][CH:14]=2)[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1>C(O)C>[C:3]1([C:9]2[CH:10]=[C:11]([C:15]([NH:17][C:18]3[CH:26]=[C:25]([C:27]4[CH:31]=[CH:30][S:29][CH:28]=4)[CH:24]=[CH:23][C:19]=3[C:20]([O-:22])=[O:21])=[O:16])[CH:12]=[N:13][CH:14]=2)[CH:4]=[CH:5][CH:6]=[CH:7][CH:8]=1.[Na+:2]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 58508812HCID 58508812, compound

Product 1

HCID 58508811HCID 58508811, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A 1 mol/L aqueous solution of sodium hydroxide (0.10 mL) was added to an ethanol (4.0 mL) suspension of the obtained 2-(5-phenylpyridine-3-carboxamido)-4-(thiophen-3-yl)benzoic acid (47 mg) at room temperature, followed by stirring at the same temperature for 1 hour and 10 minutes. The solvent was evaporated under reduced pressure, and ethanol and water were added to the obtained residue. The solid substance was collected by filtration to obtain 40 mg of sodium 2-(5-phenylpyridine-3-carboxamido)-4-(thiophen-3-yl)benzoate as a white solid.

Workup

  1. customThe solvent was evaporated under reduced pressure, and ethanol and water
  2. additionwere added to the obtained residue
  3. filtrationThe solid substance was collected by filtration

Sources & evidence

ORD record
ord-2362cc3967db42eaade20b374085e9bd
Source dataset
uspto-grants-2013_07
Patent number
US08492582B2

Reaction notes

Loading…