Sodium Hydroxide → HCID 58508715, compound

HRID 454779Notes

Reaction equation

HRID 454779 reaction equation
O1CCOCC1.[OH-].[Na+:8].[C:9]1([C:15]2[CH:23]=[CH:22][C:18]([C:19]([OH:21])=[O:20])=[C:17]([NH:24][C:25]([C:27]3[CH:28]=[N:29][C:30]([C:33]4[CH:38]=[CH:37][N:36]=[CH:35][CH:34]=4)=[CH:31][CH:32]=3)=[O:26])[CH:16]=2)[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1>CO>[C:9]1([C:15]2[CH:23]=[CH:22][C:18]([C:19]([O-:21])=[O:20])=[C:17]([NH:24][C:25]([C:27]3[CH:28]=[N:29][C:30]([C:33]4[CH:34]=[CH:35][N:36]=[CH:37][CH:38]=4)=[CH:31][CH:32]=3)=[O:26])[CH:16]=2)[CH:10]=[CH:11][CH:12]=[CH:13][CH:14]=1.[Na+:8]

Participants

5

Reactant 3

HCID 14798Sodium HydroxideHCID 312751,4-DioxaneHCID 58508716HCID 58508716, compound

Product 1

HCID 58508715HCID 58508715, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Dioxane (2 mL), methanol (2 mL), and a 2 mol/L aqueous solution of sodium hydroxide (0.025 mL) were added to the obtained 4-phenyl-2-(6-(pyridin-4-yl)pyridine-3-carboxamido)benzoic acid (20 mg), and the solvent was evaporated under reduced pressure. Acetone was added to the obtained residue. The solid substance was collected by filtration to obtain 17 mg of sodium 4-phenyl-2-(6-(pyridin-4-yl)pyridine-3-carboxamido)benzoate as a yellow solid.

Workup

  1. customthe solvent was evaporated under reduced pressure
  2. additionAcetone was added to the obtained residue
  3. filtrationThe solid substance was collected by filtration

Sources & evidence

ORD record
ord-b0bf01f1ce2949f0a9ebd60641c1bf5b
Source dataset
uspto-grants-2013_07
Patent number
US08492582B2

Reaction notes

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