HRID4549

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：COCCOc1ccc(OCC(O)CN(CCCCOc2ccc(O)c(C(N)=O)c2)Cc2ccccc2)cc1

HCID54025247

未命名化合物

PRODUCTS

生成物

结构：COCCOc1ccc(OCC(O)CNCCCCOc2ccc(O)c(C(N)=O)c2)cc1

HCID13754392

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID887

Methanol

CH4O

PROCEDURE

实验过程

A solution of 25 g of crude 1-[N-[4-(3-carbamoyl-4-hydroxyphenoxy)butyl]benzylamino]-3-[4-(2-methoxyethoxy)phenoxy]propan-2-ol in 250 ml of methanol is hydrogenated and worked up analogously to Example 4. The resulting crystalline crude product is recrystallised from isopropanol and yields 1-[4-(3-carbamoyl-4-hydroxyphenoxy)butylamino]-3-[4-(2-methoxyethoxy)phenoxy]propan-2-ol having a melting point of 122°-124°.

WORKUP

后处理

customThe resulting crystalline crude product is recrystallised from isopropanol