Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 4549Generated: October 28, 2026

1-[N-[4-(3-carbamoyl-4-hydroxyphenoxy)butyl]benzylamino]-3-[4-(2-methoxyethoxy)-phenoxy]propan-2-ol → HCID 13754392, compound

https://huagongshe.com/reaction/4549

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-[N-[4-(3-carbamoyl-4-hydroxyphenoxy)butyl]benzylamino]-3-[4-(2-methoxyethoxy)-phenoxy]propan-2-olHCID 54025247—
SolventMethanolHCID 887—
ProductHCID 13754392HCID 13754392—

Reaction Steps

A solution of 25 g of crude 1-[N-[4-(3-carbamoyl-4-hydroxyphenoxy)butyl]benzylamino]-3-[4-(2-methoxyethoxy)phenoxy]propan-2-ol in 250 ml of methanol is hydrogenated and worked up analogously to Example 4. The resulting crystalline crude product is recrystallised from isopropanol and yields 1-[4-(3-carbamoyl-4-hydroxyphenoxy)butylamino]-3-[4-(2-methoxyethoxy)phenoxy]propan-2-ol having a melting point of 122°-124°.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04727067
Source datasetuspto-grants-1988_02
ORD IDord-2ae538c41730482c9160ea66680d7309
Source noteuspto-grants-1988_02