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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 454911Generated: October 30, 2026

Hydrochloric Acid → HCID 86660173, compound

https://huagongshe.com/reaction/454911

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 58548116HCID 58548116—
SolventMethanolHCID 887—
ProductHCID 86660173HCID 8666017395%

Reaction Steps

To tert-butyl 4-((3-(tetrahydro-2H-pyran-4-yl)pyridin-2-yl)oxy)piperidine-1-carboxylate (3.2 g, 8.8 mmol) was added 4 M HCl in MeOH (100 mL). The solution was stirred at room temperature for 2 hours. The solvent was removed under reduced pressure to give the title compound (2 g, 9.8 mmol, yield 95%). ESI-MS (M+1): 263 calc. for C15H22N2O2 262.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08497265B2
Source datasetuspto-grants-2013_07
ORD IDord-8ca9bbbefce04742be92647ebedbba5d
Source noteuspto-grants-2013_07