反应详情

To a solution of {(R)-2-Hydroxy-1-[4-(2-methyl-pentyloxy)-phenyl]-ethyl}-carbamic acid t-butyl ester (0.70 g 2.08 mmol), in dichloromethane (10 ml) in an ice bath was added 4 M HCl in 1,4-dioxane (10 ml). The final mixture was then stirred at room temperature for 1.5 hrs. The excessive solvent was removed in vacuum to give a white solid, which was used directly for next step.

1. customThe excessive solvent was removed in vacuum
2. customto give a white solid, which