反应详情

The title compound was prepared according to Method A and the experimentals described for compound 1 from 3-(chloromethyl)-2-(4-chlorophenyl)imidazo[1,2-a]pyridine hydrochloride and methyl indoline-2-carboxylate. M/e+ 418 for C24H21ClN3O2 (M+H)+; 1H-NMR (400 MHz, CDCl3) δ 8.33 (d, J=6.9 Hz, 1H), 7.69 (d, J=8.4 Hz, 2H), 7.64 (d, J=9.1 Hz, 1H), 7.64 (d, J=8.4 Hz, 2H), 7.25 (t, J=6.9 Hz, 1H), 7.09 (t, J=7.7 Hz, 1H), 7.04 (d, J=6.9 Hz, 1H), 6.83 (t, J=6.6 Hz, 1H), 6.75 (t, J=7.7 Hz, 1H), 6.60 (d, J=7.7 Hz, 1H), 4.90 (d, J=14.7 Hz, 1H), 4.62 (d, J=14.7 Hz, 1H), 3.85 (t, J=8.4 Hz, 1H), 3.26 (m, 1H), 3.23 (s, 3H), 2.96 (dd, J=15.7, 8.0 Hz, 1H) ppm.