3-((1H-imidazol-1-yl)methyl)-6-methyl-2-p-tolylimidazo[1,2-a]pyridine → 3-((1H-tetrazol-1-yl)methyl)-2-(4-chlorophenyl)imidazo[1,2-a]pyridine

Participants

Reaction Steps

The title compound was prepared according to Method A and the experimentals described for compound 1 from 3-(chloromethyl)-2-(4-chlorophenyl)imidazo[1,2-a]pyridine hydrochloride and 1H-tetrazole. M/e+ 311 for C15H12ClN6 (M+H)+; 1H-NMR (400 MHz, CDCl3) δ 8.45 (s, 1H), 8.12 (d, J=6.9 Hz, 1H), 7.73 (d, J=9.1 Hz, 1H), 7.64 (d, J=8.4 Hz, 2H), 7.50 (d, J=8.4 Hz, 2H), 7.37 (td, J=6.9, 1.1 Hz, 1H), 6.97 (m, 1H), 6.03 (s, 2H) ppm.

Provenance & Evidence