HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 67028888, compound → 1-((2-(4-chlorophenyl)-6-fluoroimidazo[1,2-a]pyridin-3-yl)methyl)pyridin-2(1H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 67028888 | HCID 67028888 | — |
| Reactant | HCID 178516071 | HCID 178516071 | — |
| Product | 1-((2-(4-chlorophenyl)-6-fluoroimidazo[1,2-a]pyridin-3-yl)methyl)pyridin-2(1H)-one | HCID 67029125 | — |
Reaction Steps
The title compound was prepared according to Method B and the experimentals described for compound 91 from 3-(chloromethyl)-2-(4-chlorophenyl)-6-fluoroimidazo[1,2-a]pyridine hydrochloride and pyridin-2-ol. 1H-NMR (CDCl3, 400 MHz, δ) 8.45 (dd, J=2.4, 4.0 Hz, 1H), 7.65 (d, J=8.4 Hz, 2H), 7.58 (dd, J=5.1, 9.8 Hz, 1H), 7.46 (d, J=8.4 Hz, 1H), 7.24 (m, 1H), 7.16 (m, 1H), 6.76 (dd, J=1.9, 6.9 Hz, 1H), 6.59 (d, J=9.1 Hz, 1H), 6.00 (m, 1H), 5.62 (s, 2H) ppm; me/354 (M+H)+
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08497278B2 |
| Source dataset | uspto-grants-2013_07 |
| ORD ID | ord-38e44377a4c44c31b0e34589a7de3e86 |
| Source note | uspto-grants-2013_07 |