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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 455074Generated: October 29, 2026

Methylamine → HCID 67029123, compound

https://huagongshe.com/reaction/455074

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethylamineHCID 6329—
ReactantHCID 58337018HCID 58337018—
ReactantHCID 67028967HCID 67028967—
ProductHCID 67029123HCID 67029123—

Reaction Steps

The title compound was prepared according to the experimental for compound 132 from 4-chloro-1-((2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl)methyl)pyrimidin-2(1H)-one and methylamine. M/e− 366 for C19H17ClN5O (M+H)+; 1H-NMR (400 MHz, CDCl3) δ 8.42 (d, J=6.6 Hz, 1H), 7.68 (d, J=8.4 Hz, 2H), 7.62 (m, 1H), 7.46 (d, 8.4 Hz, 2H), 7.28 (d, J=7.7 Hz, 1H), 6.86 (t, J=6.9 Hz, 1H), 6.64 (d, J=7.3 Hz, 1H), 5.51 (s, 2H), 5.41 (d, J=7.3 Hz, 1H), 5.24 (bs, 1H), 2.98 (s, 3H) ppm.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08497278B2
Source datasetuspto-grants-2013_07
ORD IDord-fb54633c0b594d899a327e16f6a66931
Source noteuspto-grants-2013_07