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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 455078Generated: October 30, 2026

Sodium ethoxide → HCID 67028969, compound

https://huagongshe.com/reaction/455078

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium ethoxideHCID 2723922—
ReactantHCID 58337018HCID 58337018—
ReactantHCID 67028967HCID 67028967—
SolventEthanolHCID 702—
ProductHCID 67028969HCID 67028969—

Reaction Steps

The title compound was prepared according to the experimental for compound 132 from 4-chloro-1-((2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl)methyl)pyrimidin-2(1H)-one and NaOEt in EtOH. M/e+ 381 for C20H18ClN4O2 (M+H)+; 1H-NMR (400 MHz, CDCl3) δ 8.36 (d, J=7.0 Hz, 1H), 8.17 (s, 1H), 7.66 (d, J=8.4 Hz, 2H), 7.48 (d, J=8.4 Hz, 2H), 7.30 (m, 1H), 6.92 (m, 1H), 6.89 (d, J=6.9 Hz, 1H), 5.71 (d, J=6.9 Hz, 1H), 5.60 (s, 2H), 4.40 (q, J=6.9 Hz, 2H), 1.32 (t, J=6.9 Hz, 3H) ppm.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08497278B2
Source datasetuspto-grants-2013_07
ORD IDord-8e2aca9e82e14045b20fc27617e2b8d9
Source noteuspto-grants-2013_07