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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 455086Generated: October 29, 2026

2-Amino-4-chloro-6-methylpyrimidine → HCID 86655121, compound

https://huagongshe.com/reaction/455086

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-4-chloro-6-methylpyrimidineHCID 21810—
ReactantHCID 67028972HCID 67028972—
ProductHCID 86655121HCID 86655121—

Reaction Steps

The title compound was prepared according to Method A and the experimentals described for compound 139 from 4-(6-chloro-3-(chloromethyl)imidazo[1,2-a]pyridin-2-yl)benzonitrile hydrochloride and 4-chloro-6-methylpyrimidin-2-amine. m/e+ 409.0, 411.0 for C20H14Cl2N6; H-NMR (400 MHz, CDCl3) 8.80 (s, 1H), 7.953 (d, J=8.277 Hz, 2H), 7.750 (d, J=8.093 Hz, 2H), 7.593 (d, J=9.533 Hz, 1H), 7.234 (d, J=9.551 Hz, 1H), 6.545 (s, 1H), 5.257 (s, NH), 5.03 (d, J=5.498 Hz, 2H, D, CH2), 2.311 (s, 6H, D, 2CH3) ppm.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08497278B2
Source datasetuspto-grants-2013_07
ORD IDord-49c6f4bdb6344fe2b943161a3d416a04
Source noteuspto-grants-2013_07