2-Amino-4,6-difluoropyrimidine → N-((6-chloro-2-phenylimidazo[1,2-a]pyridin-3-yl)methyl)-4,6-difluoropyrimidin-2-amine

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	2-Amino-4,6-difluoropyrimidine	HCID 1201480	—
Edukt	6-Chloro-3-(chloromethyl)-2-phenylimidazo[1,2-a]pyridine hydrochloride	HCID 67028729	—
Produkt	N-((6-chloro-2-phenylimidazo[1,2-a]pyridin-3-yl)methyl)-4,6-difluoropyrimidin-2-amine	HCID 67028695	43%

Reaktionsschritte

The title compound was prepared according to Method A and the experimentals described for compound 139 from 6-chloro-3-(chloromethyl)-2-phenylimidazo[1,2-a]pyridine hydrochloride and 4,6-difluoropyrimidin-2-amine. ((0.26 g, 43% yield), M/e+ 372.2 for C18H12ClF2N5 (M+H)+.

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US08497278B2
Quelldatensatz	uspto-grants-2013_07
ORD ID	ord-e31a4547f64a4654a121251ee30d347b
Quellennotiz	uspto-grants-2013_07