Prolinol, (R)- → (R)-(1-(2-((6-chloro-2-phenylimidazo[1,2-a]pyridin-3-yl)methylamino)pyrimidin-4-yl)pyrrolidin-2-yl)methanol

Participants

Role	Name	HCID	Charge
Reactant	Prolinol, (R)-	HCID 2724541	—
Reactant	1-(2-((6-Chloro-2-phenylimidazo[1,2-a]pyridin-3-yl)methylamino)pyrimidin-4-yl)-4-methylpiperidin-4-ol	HCID 67029099	—
Reactant	4-chloro-N-((6-chloro-2-phenylimidazo[1,2-a]pyridin-3-yl)methyl)pyrimidin-2-amine	HCID 86655125	—
Product	(R)-(1-(2-((6-chloro-2-phenylimidazo[1,2-a]pyridin-3-yl)methylamino)pyrimidin-4-yl)pyrrolidin-2-yl)methanol	HCID 67028784	—

Reaction Steps

The title compound was prepared in the same fashion as that described for compound 187 from 4-chloro-N-((6-chloro-2-phenylimidazo[1,2-a]pyridin-3-yl)methyl)pyrimidin-2-amine and (R)-pyrrolidin-2-ylmethanol. m/e 435 (M+H)+.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08497278B2
Source dataset	uspto-grants-2013_07
ORD ID	ord-8e6420642efd4fafb51f69ab3d7608ba
Source note	uspto-grants-2013_07