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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 455152Generated: October 29, 2026

Piperidine → HCID 67028821, compound

https://huagongshe.com/reaction/455152

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPiperidineHCID 8082—
ReactantHCID 67028741HCID 67028741—
ReactantHCID 67029115HCID 67029115—
ProductHCID 67028821HCID 67028821—

Reaction Steps

The title compound was prepared according to the experimental for compound 237 from 1-((2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl)methyl)-4-methoxy-1H-pyrrol-2(5H)-one and piperidine. (62 mg, 54%) m/e+=407 (M+H+). 1H-NMR (400 MHz, CDCl3, δ): 8.49 (d, 1H, D, J=7.0 Hz), 7.73 (d, 2H, D, J=8.4 Hz), 7.62 (d, 1H, D, J=9.2 Hz), 7.47 (d, 2H, D, J=8.4 Hz), 7.25 (t, 1H, D, J=7.3 Hz), 6.85 (t, 1H, D, J=7.3 Hz), 5.09 (s, 2H), 4.69 (s, 1H), 3.56 (s, 2H), 2.99 (m, 4H), 1.63 (m, 2H), 1.53 (m, 4H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08497278B2
Source datasetuspto-grants-2013_07
ORD IDord-aa009037f50c4e029770b3815013df93
Source noteuspto-grants-2013_07